Wolfram Computation Meets Knowledge

Wolfram Innovator Award

Wolfram technologies have long been a major force in many areas of industry and research. Leaders in many top organizations and institutions have played a major role in using computational intelligence and pushing the boundaries of how the Wolfram technology stack is leveraged for innovation across fields and disciplines.

We recognize these deserving recipients with the Wolfram Innovator Award, which is awarded at the Wolfram Technology Conferences around the world.

Presented at the Wolfram Technology Conferences. Learn more

2021

Houston Methodist Research Institute

Areas: Biomedical Research, Biostatistics, Biotechnology, Mathematical Biology, Mathematical Modeling

Houston Methodist is a leading academic medical center that takes a multidisciplinary approach to changing the face of medicine. Doctors Cristini, Butner and Wang are a team of engineer scientists at the Houston Methodist Research Institute who use mathematical modeling to study biological problems, with a special focus on disease progression and treatment. They design and implement mathematical descriptions of the key biophysical phenomena within the tumor microenvironment. They are currently working to establish methods to use mathematical modeling to predict cancer-patient response to immune checkpoint inhibitor immunotherapy. Mathematica has played a key role in this process, allowing them to rapidly implement and update model versions, perform testing and optimization, and conduct extensive analysis on large sets of patient data.

Award accepted by Dr. Joseph D. Butner, faculty fellow, Mathematics in Medicine program; Dr. Vittorio Cristini, professor and director, Mathematics in Medicine program; and Dr. Zhihui Wang, research scientist and associate professor, Mathematics in Medicine program.

2017

Dr. Massimo Fazio

Professor, University of Alabama at Birmingham

Areas: Biotechnology, Image Processing, Mechanical Engineering

Dr. Fazio is an assistant professor at the University of Alabama at Birmingham whose main focus is optical imaging. His research using Wolfram technologies led to several significant NIH grants, including the 2017 Xtreme Research Award from Heidelberg Engineering at the Association for Research in Vision and Ophthalmology (ARVO) meeting. This award was granted to Dr. Fazio for creating a custom clinical imaging protocol for glaucoma patients that provides an estimate of the eye-specific mechanical response to time-varying intraocular pressure. Additionally, he created an image processing algorithm that quantifies the 3D structure of the optic nerve from OCT clinical data entirely in the Wolfram Language.

2013

Stefan Braun

Managing Director of SmartCAE

Areas: Aerospace, Biotechnology, Chemical Engineering, Control, Data Mining and Analysis, Engineering, Finance, Financial Risk, High-Performance and Parallel Computing, Image Processing, Industrial Engineering, Interface Design, Materials Science, Mathematica Consulting, Mechanical Engineering, Pharmaceutical, Physics, Risk Analysis, Signal Processing, Structural Engineering

Stefan Braun is recognized for using Mathematica in industrial applications. He has used Mathematica and the SmartCAEFab in more that 150+ industrial projects in different application areas. SmartCAE’s software solutions allow practical users to simulate complex applications problems, with a lot of parameters, without being a simulation or Mathematica expert.

2013

Brian Frezza & Emerald Therapeutics

Co-CEO and Co-founder, Emerald Therapeutics

Areas: Biotechnology

Brian Frezza, Co-CEO and Co-founder of Emerald Therapeutics, has integrated Mathematica at many organizational levels within the company—from using it as a standard documentation tool for the Emerald Therapeutics computer platform to controlling laboratory robots. Although the business is small, Mathematica has been broadly integrated in a manner rarely seen, even by Mathematica’s power users. Emerald’s small team has used Mathematica to conduct more than half a million biotech experiments.

2013

Bart ter Haar Romeny

Eindhoven University of Technology

Areas: Biotechnology, Image Processing, Mathematics

A professor in biomedical image analysis, Bart ter Haar Romeny uses Mathematica to design brain-inspired image analysis methods for computer-aided diagnosis. He is an enthusiastic teacher, and introduced Mathematica as a design tool in the curriculum for all students of his department and in most projects in his group. He advocates that Mathematica is ideal for designing innovative algorithms and for “playing with the math.” His PhD students van Almsick, Duits, Franken, (now Professor) Florack, Janssen, and Bekkers substantially contributed to the Mathematica packages on brain-inspired computing. He cochaired with Markus van Almsick the International Mathematica Symposium 2008 in Maastricht and teaches a popular national course on biologically inspired computing (book written in Mathematica), which was thrice awarded the BME Teaching Award.

2012

Robert B. Nachbar

Mathematician, Chemist, Biologist, Modeling & Simulation; Merck Research Laboratories

Areas: Biology, Biotechnology, Pharmaceutical

Robert Nachbar is recognized for using Mathematica at Merck. He was instrumental in the Gardasil HPV vaccine project, turning a research-grade model created by his coworkers Elamin Elbasha and Erik Dasbach into a production-grade simulation package. Robert is responsible for the Wolfram|Alpha trial at Merck, has used Mathematica frequently in his research on viral dynamics for the hepatitis C virus, and has modeled clinical trial data.

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